Daya Antibakteri Infusa Kulit Manggis (Garcinia mangostana L) terhadap Streptococcus mutans (Antibacterial of Mangosteen peel infuse (Garcinia mangostana L ) Against Streptococcus mutans)
Abstract
One of the main causes of dental caries is Streptococcus mutans. Some sources
mentioned in the mangosteen peel contains flavonoids, saponins and tannins which
have antibacterial activity. The purpose of this research was to determine the
antibacterial activity of mangosteen peel infuse against S.mutans, the most effective
inhibition and minimum inhibition. The sample was divided into 10 groups: negative
control (K), positive control (K +), and the treatment group of infusa mangosteen rind
with concentration of 100%, 50%, 25%, 12.5%, 6.25%, 3.13%, 1.56% and 0.78%.
Negative control group only containing BHI-B. Positive control group containing BHI-B,
S.mutans and Tetracycline hydrochloride. The treatment groups containing BHI-B, S.
mutans and different concentration of each group. S.mutans colonies was counted using
a colony counter. Data were analyzed with the Kruskal Wallis test followed by Mann-
Whitney test. Results of this research showed that infuse mangosteen rind was effective
as an antibacterial. The most effective concentration which can inhibit S.mutans colonies
was 100% and the minimum concentration was 0.78%.
Keywords: Mangosteen peel infuse, antibacteria, Streptococcus mutans, Tetracycline
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