Aktivitas Antibakteri Kombinasi Vitamin C dan Amoksisilin sebagai Bahan Alternatif Intrakanal Medikamen terhadap Enterococcus faecalis secara In Vitro

  • Julia Eka Putri Ayuningtyas Fakultas Kedokteran Gigi Universitas Jember
  • Pudji Astuti Fakultas Kedokteran Gigi Universitas Jember
  • Dwi Warna Aju Fatmawati Fakultas Kedokteran Gigi Universitas Jember

Abstract

Bacteria that are often found in cases of pulp necrosis and root canal treatment are Enterococcus faecalis. Elimination of microorganisms in the root canal can use intracanal medicament. The intracanal medicament can be used from antibiotics such as amoxicillin. The antibacterial power of amoxicillin can be increased by combination with vitamin C to prevent resistance. This research aimed to determine the zone of inhibition of vitamin C and amoxicillin against Enterococcus faecalis. The method used in this study is well diffusion method. Inhibition is shown through the clear zone around the wellbore at 24 hours, 48 ​​hours, 72 hours after incubation. The number of research samples is 16 consisted of 4 groups consisting of amoxicillin, vitamin C, a combination of vitamin C and amoxicillin, and 3 MIX MP. The data were tested by non-parametric statistical analysis Kruskal Wallis and Mann Whitney. The result showed that vitamin C and amoxicillin's antibacterial activity as alternative material intracanal medicament is equivalent to antibacterial 3 MIX MP.

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Published
2021-01-16
How to Cite
AYUNINGTYAS, Julia Eka Putri; ASTUTI, Pudji; FATMAWATI, Dwi Warna Aju. Aktivitas Antibakteri Kombinasi Vitamin C dan Amoksisilin sebagai Bahan Alternatif Intrakanal Medikamen terhadap Enterococcus faecalis secara In Vitro. Pustaka Kesehatan, [S.l.], v. 9, n. 1, p. 60-65, jan. 2021. ISSN 2721-3218. Available at: <https://jurnal.unej.ac.id/index.php/JPK/article/view/19794>. Date accessed: 01 aug. 2021. doi: https://doi.org/10.19184/pk.v9i1.19794.