Efek Seduhan Kopi Robusta terhadap Jumlah Limfosit pada Daerah Tarikan Ligamen Periodontal Gigi Marmut (Cavia Cobaya) yang  Diinduksi Gaya Mekanis Ortodonti

Ginanjar Hidayatullah; Herniyati Herniyati; Leliana Sandra Deviade Putri

doi:10.19184/pk.v7i3.11560

Ginanjar Hidayatullah student
Herniyati Herniyati Bagian Ortodonsia, Fakultas Kedokteran Gigi, Universitas Jember
Leliana Sandra Deviade Putri Bagian Ortodonsia, Fakultas Kedokteran Gigi, Universitas Jember

DOI: https://doi.org/10.19184/pk.v7i3.11560

Abstract

Malocclusion is an occlusion that deviates from the normal state, so it needs to be treated using an orthodontic device. The formation of new alveolar bone after obtaining an orthodontic force will be surrounded by osteoid bones are not stable enough (relapse). Robusta coffee (Coffea robusta) has flavonoids which can increase lymphocyte proliferation. The purpose of this study was to analyze the effect of robusta coffee on the number of lymphocyte cells in the tension area of marmot’s (Cavia cobaya) periodontal ligament which induced by mechanical orthodontic forces. This type of research is laboratory experimental with the Post Test Only Control Group Design. The average number of lymphocyte cells in group A = 0.75, B = 1.45, C = 1.26, D = 1.54. One-way Anova test results showed that the number of lymphocyte cells in all groups showed a significant difference (p <0.05). The results of the post hoc LSD test showed that group A had significant differences with group B and group D (p <0.05). While group C did not have a significant difference with group A (p> 0.05). The conclusion obtained is that the provision of robusta coffee brew for 2 weeks can increase the number of lymphocyte cells in the tension area of marmot’s (Cavia cobaya) periodontal ligament which induced by orthodontic mechanical forces compared to without robusta coffee brew.

References

[1] Graber TM, Swain, BF. Orthodontic Current Principles and Techniques Sixth Edition. St. Louis: Mosby Company. 2017.
[2] Wahyuningsih S, et al. Perawatan maloklusi angle klas I dengan gigi depan crowding berat dan cross bite menggunakan teknik Begg pada pasien dengan kebersihan mulut buruk. Majalah Kedokteran Gigi. 22014; 1(2): 204 – 211.
[3] Souza RA, Oliveira AF, Pinheiro SMS, Cardoso JP, Magnani MBBA. Expectations of orthodontic treatment in adults: The conduct in orthodontist patient relationship. Dental Press J Orthod. 2013; 18(2): 88-94.
[4] Utari TR, Soehardono. Pergerakan gigi dan remodelling tulang maksila regio anterior di akhir perawatan ortodontik teknik Begg maloklusi angle klas I dengan insisivus maksila protusif. Mutiara Medika. 2007; 7(2): 57-60.
[5] Iskandar P, Patricia. Peran prostaglandin pada pergerakan gigi ortodontik. Dentofasial. 2010; 9(2): 91-100.
[6] Amin MN, Permatasari N. Aspek biologis pergerakan gigi secara ortodonsi. Stomatognatic (J. K. G Unej). 2016; 13 (1): 22-27.
[7] Iswari H. Relaps dan pencegahannya dalam ortodonti. WIDYA. 2012; 29(319): 53-58.
[8] Liu Y, Zhang T, Zhang C, Jin SS, Yang RL, Wang XD, et al., Aspirin blocks orthodontic relapse via inhibition of CD4+ T lymphocytes. Journal of Dental Reseacrh. 2017; 1-9.
[9] Isola G. Mechanobiology of the tooth movement during the orthodontic treatment. Minerva Stomatologica. 2016; 65(5):2 99-327.
[10] Buckwalter J, Orthopaedic Basic Science Biology and Biomechanics of the Musculoskletal System 2nd edition. American Academy Orthopedic Surgeons. 2008.
[11] Wiss RA. Fracture Master Techniques in Orthopaedic Surgery, 3th edition. England: Lippicott William & Wilkins. 2011.
[12] Harahap, Ridwan M. Identifikasi daging buah kopi robusta (Coffea Robusta) berasal dari provinsi Aceh. Journal of Islamic Science and Technology. 2017; 3(2).
[13] Nugroho, Astuti Y. Efek pemberian kombinasi buah sirih (Piper betle L), daun miyana (Plectranthus scutellarioides (L.) R. BR.), madu dan kuning telur terhadap peningkatan aktivitas dan kapasitas fagositosis sel makrofag. Media Litbang Kesehatan. 2012; 22(1).
[14] Budirahardjo R. Potensi imunomodulator biji kopi robusta terhadap karies gigi. Skripsi. Universitas Jember. 2016.
[15] Badan Penelitian dan Pengembangan Kesehatan. Inventaris Tanaman Obat Indonesia. Jakarta: Departemen Kesehatan & Kesejahteraan Sosial RI. 2000.
[16] Kenisa, 2012. Effect of Robusta coffee beans ointment on full thickness wound healing. Majalah Kedokteran Gigi. 2012; 45(1): 52-57
[17] Geahlen RL, Koonchanok NM, McLaughlin JL. Inhibition of proteintyrosine kinase activity by flavonoids and related compounds. J Nat Prod. 1989; 52: 982– 986.
[18] Izquierdo M, Cantrell DA. Protein tyrosine kinases couple the interleukin-2 receptor to p21ras. European Journal of Immunology. 1993; 23(1): 131–135.
[19] Herniyati. Effects of Robusta coffee (Coffea canephora) brewing on levels of RANKL and TGF- β1 in orthodontic tooth movement. Majalah Kedokteran Gigi). 2016; 49(3): 143–147.
[20] Andrade Jr, Ildeu. Inﬂammation and tooth movement: the role of cytokines, chemokines, and growth factor. Seminars in Orthodontics. 2012; 18(4): 257-269.