Pengaruh Hemodialisis terhadap Fungsi Diastolik Ventrikel Kiri pada Pasien Penyakit Ginjal Kronik Stadium V
Abstract
Stage V chronic kidney disease (CKD) patients need renal replacement therapy. Hemodialysis is main choice for renal replacement therapy and correlates with changes of left ventricular function. Left ventricular diastolic function is one parameter of left ventricular function. The aim of this study was to analyze the effect of hemodialysis towards left ventricular diastolic function in stage V CKD patients at RSD dr. Soebandi Jember. This study included 30 patients (17 female, age 48,20±8,02 years) and underwent echocardiography 30 min before and after a hemodialysis session. Sample characteristics were divided into sex, age, duration of hemodialysis, blood pressure before and after hemodialysis. Diastolic function was measured with E/E’ ratio. Diastolic function criteria of 16 samples (53,5%) were normal (E/E’ ratio <10) after doing a hemodialysis session. Mean ratio E/E’ was significantly reduced (13,09±4,55 vs 11,6±5,04, p<0,05). In conclusion, hemodialysis could increase left ventricular diastolic function in stage V CKD patients at RSD dr. Soebandi Jember.
References
[1] Kementerian Kesehatan Republik Indonesia. Riset Kesehatan Dasar: RISKESDAS. Jakarta: Balitbang Kemenkes RI; 2013.
[2] Suwitra K. Penyakit ginjal kronik. In: Sudoyo, et al, editor. Buku Ajar Ilmu Penyakit Dalam Jilid II. Jakarta: Pusat Penerbitan Departemen Penyakit Dalam Fakultas Kedokteran Universitas Indonesia; 2014. p 2159-2165.
[3] Ortiz A, Covic A, Fliser D, Fouque D, Goldsmith D, Kanbay M, Mallamaci F, Massy ZA, Rossignol P, Vanholder R, Wiecek A. Epidemiology, contributors to, and clinical trials of mortality risk in chronic kidney failure. The Lancet. 2014 May 30; 383(9931): 1831-43.
[4] Persatuan Nefrologi Indonesia [Internet]. Jakarta: Persatuan Nefrologi Indonesia; 2015 [cited 2017 September 13]. Available from: http://www.pernefri-inasn.org/
[5] Anand S, Bitton A, Gaziano T. The gap between estimated incidence of end-stage renal disease and use of therapy. PLoS One. 2013 Aug 30; 8(8): 72860.
[6] Foundation NK. KDOQI clinical practice guideline for hemodialysis adequacy: 2015 update. American Journal of Kidney Diseases. 2015 Nov 30; 66(5): 884-930.
[7] Saran R, Robinson B, Abbott KC, Agodoa LY, Albertus P, Ayanian J, Balkrishnan R, Bragg-Gresham J, Cao J, Chen JL, Cope E. US renal data system 2016 annual data report: epidemiology of kidney disease in the United States. American Journal of Kidney Diseases. 2017 Mar 1; 69(3): 7-8.
[8] de Jager DJ, Grootendorst DC, Jager KJ, van Dijk PC, Tomas LM, Ansell D, Collart F, Finne P, Heaf JG, De Meester J, Wetzels JF. Cardiovascular and noncardiovascular mortality among patients starting dialysis. JAMA. 2009 Oct 28; 302(16): 1782-9.
[9] Sood MM, Pauly RP, Rigatto C, Komenda P. Left ventricular dysfunction in the haemodialysis population. NDT Plus. 2008 Aug; 1(4): 199-205.
[10] Losi MA, Memoli B, Contaldi C, Barbati G, Del Prete M, Betocchi S, Cavallaro M, Carpinella G, Fundaliotis A, Parrella LS, Parisi V. Myocardial fibrosis and diastolic dysfunction in patients on chronic haemodialysis. Nephrology Dialysis Transplantation. 2010 Jan 14; 25(6): 1950-4.
[11] Liu YW, Su CT, Song EJ, Tsai WC, Li YH, Tsai LM, Chen JH, Sung JM. The role of echocardiographic study in patients with chronic kidney disease. Journal of the Formosan Medical Association. 2015 Sep 30; 114(9): 797-805.
[12] Majid A. Profil Fungsi Distolik Ventrikel Kiri secara Ekokardiografi pada Gagal Jantung Kongestif. Majalah Kedokteran Nusantara. 2005; 38(1).
[13] Chinnaiyan KM, Alexander D, Maddens M, McCullough PA. Curriculum in cardiology: integrated diagnosis and management of diastolic heart failure. American heart journal. 2007 Feb 28;153(2): 189-200.
[14] Pecoits-Filho R, Barberato SH. Echocardiography in chronic kidney disease: diagnostic and prognostic implications. Nephron Clinical practice. 2010; 114(4): 242-247.
[15] Oemar, H. Textbook of Echocardiography Interpretasi dan Diagnosis Klinik. Jakarta: Yayasan Mencerdaskan Bangsa; 2005.
[16] Stróżecki P, Adamowicz A, Nartowicz E, Odrowąż-Sypniewska G, Włodarczyk Z, Manitius J. Parathormon, calcium, phosphorus, and left ventricular structure and function in normotensive hemodialysis patients. Renal Failure. 2001 Jan 1; 23(1): 115-26.
[17] Ito S, Yoshida M. Protein-bound uremic toxins: new culprits of cardiovascular events in chronic kidney disease patients. Toxins. 2014 Feb 20; 6(2): 665-78.
[18] Vanholder R, Schepers E, Pletinck A, Nagler EV, Glorieux G. The uremic toxicity of indoxyl sulfate and p-cresyl sulfate: a systematic review. Journal of the American Society of Nephrology. 2014 Sep 1; 25(9): 1897-907.
[19] Duran M, Unal A, Inanc MT, Esin F, Yilmaz Y, Ornek E. Effect of maintenance hemodialysis on diastolic left ventricular function in end-stage renal disease. Clinics. 2010; 65(10): 979-84.
[20] Nardi E, Palermo A, Mulè G, Cusimano P, Cottone S, Cerasola G. Left ventricular hypertrophy and geometry in hypertensive patients with chronic kidney disease. Journal of hypertension. 2009 Mar 1; 27(3): 633-41.
[21] Liu, KD, Chertow GM. Dialysis in the treatment of renal failure. In Fauci, A. S., et al. Harrison’s Principles of Internal Medicine 19th Edition. Amerika Serikat: McGraw-Hill; 2015. p 1822-1825.
[22] Franczyk-Skóra B, Gluba A, Olszewski R, Banach M, Rysz J. Heart function disturbances in chronic kidney disease–echocardiographic indices. Archives of Medical Science. 2014 Dec 22; 10(6): 1109.
[23] Arshi S, Butt GU, Mian FA. Echocardiographic study of cardiac dysfunction in patients of chronic kidney disease on hemodialysis. Pakistan Armed Forces Medical Journal. 2016 Dec 1; 66(6).
[24] Cobo G, Hecking M, Port FK, Exner I, Lindholm B, Stenvinkel P, Carrero JJ. Sex and gender differences in chronic kidney disease: progression to end-stage renal disease and haemodialysis. Clinical Science. 2016 Jul 1;130(14): 1147-1163.
[25] Tokala BF, Kandou LF, Dundu AE. Hubungan antara lamanya menjalani hemodialisis dengan tingkat kecemasan pada pasien dengan penyakit ginjal kronik di RSUP Prof. Dr. RD Kandou Manado. e-CliniC. 2015; 3(1).
[26] Weinstein JR, Anderson S. The aging kidney: physiological changes. Advances in chronic kidney disease. 2010 Jul 31;17(4): 302-307.
[27] Galetta F, Cupisti A, Franzoni F, Carpi A, Barsotti G, Santoro G. Acute effects of hemodialysis on left ventricular function evaluated by tissue Doppler imaging. Biomedicine & Pharmacotherapy. 2006 Feb 28; 60(2): 66-70.
[28] Sağ S, Yeşilbursa D, Yıldız A, Dilek K, Şentürk T, Serdar OA, Aydınlar A. Acute Haemodialysis-induced Changes in Tissue Doppler Echocardiography Parameters. Balkan Medical Journal. 2014 Sep; 31(3): 239.
[29] Chertow GM, Levin NW, Beck GJ, Daugirdas JT, Eggers PW, Kliger AS, Larive B, Rocco MV, Greene T. Long-Term Effects of Frequent In–Center Hemodialysis. Journal of the American Society of Nephrology. 2015 Oct 14.
[30] Graham RJ, Gelman JS, Donelan L, Mottram PM, Peverill RE. Effect of preload reduction by haemodialysis on new indices of diastolic function. Clinical Science. 2003 Oct 1; 105(4): 499-506.
[31] Webster AC, Nagler EV, Morton RL, Masson P. Chronic kidney disease. The Lancet. 2017 Mar 31;389(10075): 1238-1252.
[32] Hung KC, Huang HL, Chu CM, Chen CC, Hsieh IC, Chang ST, Fang JT, Wen MS. Evaluating preload dependence of a novel Doppler application in assessment of left ventricular diastolic function during hemodialysis. American Journal of Kidney Diseases. 2004 Jun 30; 43(6): 1040-6.
[33] Caballero L, Kou S, Dulgheru R, Gonjilashvili N, Athanassopoulos GD, Barone D, Baroni M, Cardim N, Gomez de Diego JJ, Oliva MJ, Hagendorff A. Echocardiographic reference ranges for normal cardiac Doppler data: results from the NORRE Study. European Heart Journal-Cardiovascular Imaging. 2015 Apr 20; 16(9): 1031-41.
[34] Otsuka T, Suzuki M, Yoshikawa H, Sugi K. Left ventricular diastolic dysfunction in the early stage of chronic kidney disease. Journal of Cardiology. 2009 Oct 31; 54(2): 199-204.
[35] Iwabuchi Y, Ogawa T, Inoue T, Otsuka K, Nitta K. Elevated E/E'predicts cardiovascular events in hemodialysis patients with preserved systolic function. Internal Medicine. 2012; 51(2): 155-60.
[2] Suwitra K. Penyakit ginjal kronik. In: Sudoyo, et al, editor. Buku Ajar Ilmu Penyakit Dalam Jilid II. Jakarta: Pusat Penerbitan Departemen Penyakit Dalam Fakultas Kedokteran Universitas Indonesia; 2014. p 2159-2165.
[3] Ortiz A, Covic A, Fliser D, Fouque D, Goldsmith D, Kanbay M, Mallamaci F, Massy ZA, Rossignol P, Vanholder R, Wiecek A. Epidemiology, contributors to, and clinical trials of mortality risk in chronic kidney failure. The Lancet. 2014 May 30; 383(9931): 1831-43.
[4] Persatuan Nefrologi Indonesia [Internet]. Jakarta: Persatuan Nefrologi Indonesia; 2015 [cited 2017 September 13]. Available from: http://www.pernefri-inasn.org/
[5] Anand S, Bitton A, Gaziano T. The gap between estimated incidence of end-stage renal disease and use of therapy. PLoS One. 2013 Aug 30; 8(8): 72860.
[6] Foundation NK. KDOQI clinical practice guideline for hemodialysis adequacy: 2015 update. American Journal of Kidney Diseases. 2015 Nov 30; 66(5): 884-930.
[7] Saran R, Robinson B, Abbott KC, Agodoa LY, Albertus P, Ayanian J, Balkrishnan R, Bragg-Gresham J, Cao J, Chen JL, Cope E. US renal data system 2016 annual data report: epidemiology of kidney disease in the United States. American Journal of Kidney Diseases. 2017 Mar 1; 69(3): 7-8.
[8] de Jager DJ, Grootendorst DC, Jager KJ, van Dijk PC, Tomas LM, Ansell D, Collart F, Finne P, Heaf JG, De Meester J, Wetzels JF. Cardiovascular and noncardiovascular mortality among patients starting dialysis. JAMA. 2009 Oct 28; 302(16): 1782-9.
[9] Sood MM, Pauly RP, Rigatto C, Komenda P. Left ventricular dysfunction in the haemodialysis population. NDT Plus. 2008 Aug; 1(4): 199-205.
[10] Losi MA, Memoli B, Contaldi C, Barbati G, Del Prete M, Betocchi S, Cavallaro M, Carpinella G, Fundaliotis A, Parrella LS, Parisi V. Myocardial fibrosis and diastolic dysfunction in patients on chronic haemodialysis. Nephrology Dialysis Transplantation. 2010 Jan 14; 25(6): 1950-4.
[11] Liu YW, Su CT, Song EJ, Tsai WC, Li YH, Tsai LM, Chen JH, Sung JM. The role of echocardiographic study in patients with chronic kidney disease. Journal of the Formosan Medical Association. 2015 Sep 30; 114(9): 797-805.
[12] Majid A. Profil Fungsi Distolik Ventrikel Kiri secara Ekokardiografi pada Gagal Jantung Kongestif. Majalah Kedokteran Nusantara. 2005; 38(1).
[13] Chinnaiyan KM, Alexander D, Maddens M, McCullough PA. Curriculum in cardiology: integrated diagnosis and management of diastolic heart failure. American heart journal. 2007 Feb 28;153(2): 189-200.
[14] Pecoits-Filho R, Barberato SH. Echocardiography in chronic kidney disease: diagnostic and prognostic implications. Nephron Clinical practice. 2010; 114(4): 242-247.
[15] Oemar, H. Textbook of Echocardiography Interpretasi dan Diagnosis Klinik. Jakarta: Yayasan Mencerdaskan Bangsa; 2005.
[16] Stróżecki P, Adamowicz A, Nartowicz E, Odrowąż-Sypniewska G, Włodarczyk Z, Manitius J. Parathormon, calcium, phosphorus, and left ventricular structure and function in normotensive hemodialysis patients. Renal Failure. 2001 Jan 1; 23(1): 115-26.
[17] Ito S, Yoshida M. Protein-bound uremic toxins: new culprits of cardiovascular events in chronic kidney disease patients. Toxins. 2014 Feb 20; 6(2): 665-78.
[18] Vanholder R, Schepers E, Pletinck A, Nagler EV, Glorieux G. The uremic toxicity of indoxyl sulfate and p-cresyl sulfate: a systematic review. Journal of the American Society of Nephrology. 2014 Sep 1; 25(9): 1897-907.
[19] Duran M, Unal A, Inanc MT, Esin F, Yilmaz Y, Ornek E. Effect of maintenance hemodialysis on diastolic left ventricular function in end-stage renal disease. Clinics. 2010; 65(10): 979-84.
[20] Nardi E, Palermo A, Mulè G, Cusimano P, Cottone S, Cerasola G. Left ventricular hypertrophy and geometry in hypertensive patients with chronic kidney disease. Journal of hypertension. 2009 Mar 1; 27(3): 633-41.
[21] Liu, KD, Chertow GM. Dialysis in the treatment of renal failure. In Fauci, A. S., et al. Harrison’s Principles of Internal Medicine 19th Edition. Amerika Serikat: McGraw-Hill; 2015. p 1822-1825.
[22] Franczyk-Skóra B, Gluba A, Olszewski R, Banach M, Rysz J. Heart function disturbances in chronic kidney disease–echocardiographic indices. Archives of Medical Science. 2014 Dec 22; 10(6): 1109.
[23] Arshi S, Butt GU, Mian FA. Echocardiographic study of cardiac dysfunction in patients of chronic kidney disease on hemodialysis. Pakistan Armed Forces Medical Journal. 2016 Dec 1; 66(6).
[24] Cobo G, Hecking M, Port FK, Exner I, Lindholm B, Stenvinkel P, Carrero JJ. Sex and gender differences in chronic kidney disease: progression to end-stage renal disease and haemodialysis. Clinical Science. 2016 Jul 1;130(14): 1147-1163.
[25] Tokala BF, Kandou LF, Dundu AE. Hubungan antara lamanya menjalani hemodialisis dengan tingkat kecemasan pada pasien dengan penyakit ginjal kronik di RSUP Prof. Dr. RD Kandou Manado. e-CliniC. 2015; 3(1).
[26] Weinstein JR, Anderson S. The aging kidney: physiological changes. Advances in chronic kidney disease. 2010 Jul 31;17(4): 302-307.
[27] Galetta F, Cupisti A, Franzoni F, Carpi A, Barsotti G, Santoro G. Acute effects of hemodialysis on left ventricular function evaluated by tissue Doppler imaging. Biomedicine & Pharmacotherapy. 2006 Feb 28; 60(2): 66-70.
[28] Sağ S, Yeşilbursa D, Yıldız A, Dilek K, Şentürk T, Serdar OA, Aydınlar A. Acute Haemodialysis-induced Changes in Tissue Doppler Echocardiography Parameters. Balkan Medical Journal. 2014 Sep; 31(3): 239.
[29] Chertow GM, Levin NW, Beck GJ, Daugirdas JT, Eggers PW, Kliger AS, Larive B, Rocco MV, Greene T. Long-Term Effects of Frequent In–Center Hemodialysis. Journal of the American Society of Nephrology. 2015 Oct 14.
[30] Graham RJ, Gelman JS, Donelan L, Mottram PM, Peverill RE. Effect of preload reduction by haemodialysis on new indices of diastolic function. Clinical Science. 2003 Oct 1; 105(4): 499-506.
[31] Webster AC, Nagler EV, Morton RL, Masson P. Chronic kidney disease. The Lancet. 2017 Mar 31;389(10075): 1238-1252.
[32] Hung KC, Huang HL, Chu CM, Chen CC, Hsieh IC, Chang ST, Fang JT, Wen MS. Evaluating preload dependence of a novel Doppler application in assessment of left ventricular diastolic function during hemodialysis. American Journal of Kidney Diseases. 2004 Jun 30; 43(6): 1040-6.
[33] Caballero L, Kou S, Dulgheru R, Gonjilashvili N, Athanassopoulos GD, Barone D, Baroni M, Cardim N, Gomez de Diego JJ, Oliva MJ, Hagendorff A. Echocardiographic reference ranges for normal cardiac Doppler data: results from the NORRE Study. European Heart Journal-Cardiovascular Imaging. 2015 Apr 20; 16(9): 1031-41.
[34] Otsuka T, Suzuki M, Yoshikawa H, Sugi K. Left ventricular diastolic dysfunction in the early stage of chronic kidney disease. Journal of Cardiology. 2009 Oct 31; 54(2): 199-204.
[35] Iwabuchi Y, Ogawa T, Inoue T, Otsuka K, Nitta K. Elevated E/E'predicts cardiovascular events in hemodialysis patients with preserved systolic function. Internal Medicine. 2012; 51(2): 155-60.
Published
2020-04-26
How to Cite
RAHADIAN, Rifqi et al.
Pengaruh Hemodialisis terhadap Fungsi Diastolik Ventrikel Kiri pada Pasien Penyakit Ginjal Kronik Stadium V.
Pustaka Kesehatan, [S.l.], v. 7, n. 1, p. 8-13, apr. 2020.
ISSN 2721-3218.
Available at: <https://jurnal.unej.ac.id/index.php/JPK/article/view/17584>. Date accessed: 24 apr. 2024.
doi: https://doi.org/10.19184/pk.v7i1.17584.
Section
Articles
e-Journal Pustaka Kesehatan has CC-BY-SA or an equivalent license as the optimal license for the publication, distribution, use, and reuse of scholarly work. Authors who publish with this journal retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-ShareAlike 4.0 International License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
