The Antibacterial Activity of Infusion of Averrhoa bilimbi L Fruits and Cananga odorata Flowers against Frequently Pathogenic Bacteria
Abstract
Infectious diseases due to opportunistic bacteria and pathogens are still a health problem. Transmission can be prevented by using an alcohol-based antiseptic liquid or naturally. Averrhoa bilimbi L. fruit plants and Cananga odorata flowers contain bioactive compounds that can inhibit bacterial growth. This study aimed to analyze the infusion activity of Averrhoa bilimbi fruit and Cananga odorata flower in single and combined dosage forms against several frequently pathogenic bacteria in vitro. This posttest-only experimental study with a control group design used the paper disc diffusion method. Observation parameters were the diameter of the inhibition zone on the test bacteria after infusion treatment of 50%, 75%, and 100% A.bilimbi fruit and 100% C.odora flowers, as well as 70% alcohol. The results showed that the diameter of the inhibition zone in the combination treatment of A.bilimbi and C.odorata infusion was significantly different from that of the single preparation (p<0.05). The combination of 100% A.bilimbi and 100% C.odorata (ratio 1:1) produced the greatest effect and was equivalent to 70% alcohol. The average inhibition of the combination infusion of Staphylococcus aureus (17.36mm) and Staphylococcus epidermidis (17.57mm) was greater than that of Escherichia coli (14.48 mm) and Salmonella enterica serovar Typhi (14.12mm). In conclusion, the infusion of Averrhoa bilimbi fruit and the Cananga odorata flower had antibacterial activity, and the combined preparation produced a better inhibitory effect than the single preparation.
Keywords: antibacterial activity, Averrhoa bilimbi L., Cananga odorata, infusion, single preparation, combination preparation
References
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Budiarti, L. Y., Wydiamala, E., & Ulfa, N. (2021). Phenol Coefficient Test Combination Infusion of Cananga odorata – Averrhoa bilimbi L. Against Staphylococcus aureus and Salmonella typhi in Vitro. Bioinformatics and Biomedical Research Journal, 4(1), 19–26. https://doi.org/https://doi.org/10.11594/bbrj.04.01.03
Budiarti, L. Y., Yasmina, A., Nurikwan, P. W., Prayudi, M. O. S., Firisa, M. R., & Kangsudarmanto, Y. (2022). Antibacterial activity of infused peel of kaffir lime, manurun banana, and pineapple against the number of Staphylococcus aureus and Escherichia coli colonies. IOP Conference Series: Earth and Environmental Science, 976(1), 012034. https://doi.org/10.1088/1755-1315/976/1/012034
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Dewi, P., Ratih, G. A., Burhannuddin, B., & Sudarmanto, G. (2019). In vitro Inhibitory Activity of Ethanolic Fruit Extract from Averrhoa bilimbi L. against Streptococcus pyogenes Bacteria. Health Notions, 3(1), 13–17. https://doi.org/10.33846/hn.v3i1.276
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Fardan, I., & Harimurti, S. (2018). Formulasi Sediaan Gel Minyak Atsiri Daun Cengkeh (Syzygium aromaticum (L.) Merr. & L.M.Perry) Sebagai Antiseptik Tangan dan Uji Daya Hambat Terhadap Bakteri Staphylococcus aureus. PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia), 15(2), 218. https://doi.org/10.30595/pharmacy.v15i2.3001
Fibonacci, A., & Hulyadi, H. (2018). Uji Aktivitas Antimikroba Daun Sirsak (Annona muricata L.) Terhadap Bacillus subtillis dan Eschericia coli. Walisongo Journal of Chemistry, 1(1), 14. https://doi.org/10.21580/wjc.v2i1.2669
Hardiyanti, R., Budiarti, L. Y., & Heriyani, F. (2019). Perbedaan Jumlah Bakteri Tangan Pada Siswa Sekolah Dasar Di Sekitar Bantaran Sungai Lulut Banjarmasin Berdasarkan Teknik Mencuci Tangan. Jurnal Homeostatis, 2(1), 179–184.
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Heriyani, F., Budiarti, L. Y., Nursantari, W., & Apriliani, A. (2021). Hand Soap Activity Against the Number oOf Bacterial Colonies from the Housewife’s Hand Swab Samples in a Temporary Landfill in Kelurahan Gadang Banjarmasin. Berkala Kedokteran, 17(2), 87. https://doi.org/10.20527/jbk.v17i2.11665
Herlina, E., Widiastuti, D., & Triadi, A. (2020). POTENSI MINYAK ATSIRI BUNGA KENANGA (CANANGA ODORATA) SEBAGAI ANTIBAKTERIA DALAM SEDIAAN HAND SANITIZER GEL. EKOLOGIA, 20(2), 88–94. https://doi.org/10.33751/ekologia.v20i2.2171
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Lisnawati, N., Kumala, S., & Rahmat, D. (2019). Formulation and evaluation of antibacterial activity of nanoparticles ointment preparation using Blimbi extract. Pharmaceutical and Biomedical Research. https://doi.org/10.18502/pbr.v4i3.542
Maryam, S., Juniasti, S., & Kosman, R. (2015). UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL BUAH BELIMBING WULUH (Averrhoa bilimbi L.) ASAL KOTA WATAMPONE. Jurnal Ilmiah As-Syifaa, 7(1), 60–69. https://doi.org/10.33096/jifa.v7i1.21
Maulidya, R., Aisyah, Y., & Yunita, D. (2020). Quality Characteristics and Antibacterial Activity of Transparent Solid Soap with Addition of Cananga Oil (Cananga odorata). 112–118. https://doi.org/10.5220/0009957701120118
Mokhtar, S. I., & Abd Aziz, N. A. (2016). Antimicrobial Properties of Averrhoa bilimbi Extracts at Different Maturity Stages. Journal of Medical Microbiology & Diagnosis, 5(3). https://doi.org/10.4172/2161-0703.1000233
Nasution, R., Azwar, A. I., Helwati, H., & Marianne. (2019). Antibacterial Activities of Perfume: Combination Flower Magnolia alba, Cananga odorata and Mimusops elengi L, Fixed with Pogostemon cablin Oil. Indonesian Journal of Pharmaceutical and Clinical Research, 2(1), 19–23. https://doi.org/10.32734/idjpcr.v2i1.814
Pramiastuti, O., Rejeki, D., & Maghfiroh, I. (2020). Uji Antibakteri Kombinasi Ekstrak Daun Belimbing Wuluh (Averrhoa bilimbi L) Dan Daun Kersen (Muntingia calabura L) Terhadap Staphylococcus aureus. Parapemikir : Jurnal Ilmiah Farmasi, 9(2), 33–41. https://doi.org/10.30591/pjif.v9i2.2026
Prastiyanto, M. E., Wardoyo, F. A., Wilson, W., & Darmawati, S. (2020). Antibacterial Activity of Various Extracts of Averrhoa bilimbi against Multidrug Resistant Bacteria. Biosaintifika: Journal of Biology & Biology Education, 12(2), 163–168. https://doi.org/10.15294/biosaintifika.v12i2.23600
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Published
2022-10-31
How to Cite
BUDIARTI, Lia Yulia; WYDIAMALA, Erida; ULFA, Najiya.
The Antibacterial Activity of Infusion of Averrhoa bilimbi L Fruits and Cananga odorata Flowers against Frequently Pathogenic Bacteria.
Journal of Agromedicine and Medical Sciences, [S.l.], v. 8, n. 3, p. 182-188, oct. 2022.
ISSN 2714-5654.
Available at: <https://jurnal.unej.ac.id/index.php/JAMS/article/view/29312>. Date accessed: 24 nov. 2024.
doi: https://doi.org/10.19184/ams.v8i3.29312.
Issue
Section
Original Research Articles
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
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